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While the flow cytometric apoptosis reduction (3.48%) was not statistically significant, the molecular markers (caspase-3 down 42.7%, PARP down 77.5%, Bcl-2/Bax shift) were all highly significant

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For in vivo repair studies, histological, biomechanical, and functional endpoints should be evaluated alongside molecular mechanism markers to provide comprehensive characterisation of combination effects at tissue and molecular levels simultaneously